An asymptomatic 45-year-old man comes to the clinic because he was found to be HBsAg positive. Additional tests show: ALT 35 IU/L, AST 22 IU/L, anti-HBc positive, IgM anti-HBc negative, HBeAg negative, anti-HBe positive, HBV DNA 4250 IU/mL, anti-HDV negative, anti-HIV negative, anti-HCV negative, normal ultrasonography of upper abdomen, liver stiffness 6.8 kPa.